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Defeating Onchocerciasis (Riverblindness) in Africa
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The Onchocerciasis Control Program (OCP)
The African Program For Riverblindness Control (APOC)
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The Onchocerciasis Control Program (OCP)

OCP has been hailed as one of the most successful partnerships in the history of development assistance. Founded in 1974, OCP has an unprecedented collaboration between UN agencies. The World Bank served as the fiscal agent and WHO was the executing agency. FAO and UNDP took the lead in development planning. The Program was created with the dual mandate of controlling the disease as a public heath problem—and building local capacity to ensure continued control indefinitely—and boosting socio-economic development through long-term increases in agricultural production. The OCP has halted transmission and virtually eliminated Riverblindness throughout the eleven participating countries, and has made a major contribution towards alleviating poverty of the rural poor throughout a major sub-region of West Africa. OCP fulfilled this mandate and was closed in December of 2002, though operations continue in five Special Intervention Zones (SIZs). WHO and the World Bank will continue to serve in their respective roles. By far the largest of these zones is Sierra Leone, where operations were interrupted by a just-ended, decade-long civil war. OCP has virtually stopped transmission within the other ten West African countries where it operated. The wide-ranging benefits of this achievement include:    

OCP Governance.
Overall executive authority for OCP was vested in the Joint Programme Committee (JPC), composed of participating country representatives, donors, and sponsoring agencies. The independent Expert Advisory Committee (12 scientists) carried out annual evaluations of OCP operations, and gave technical and scientific advice to the JPC and Program Director. The Committee of Sponsoring Agencies (CSA, made up of the UNDP, FAO, WHO, and World Bank) monitored Program operations and acted as an executive secretariat, making interim decisions on behalf of the JPC throughout the year.

The Program headquarters, stationed in Ouagadougou, Burkina Faso, were comprised of 4 units: Vector Control, Epidemiological Evaluation, Bio-statistical Analysis, and Information Systems Support Administration and Support Services. Program activities were broken-down as follows: Vector Control (66%), Management and Administration (17%), and Planning, Evaluation and Transfer (PET: Devolution support activities including epidemiological evaluation, Operational research, Bio-statistics and Information systems) (17%).

A 5-member independent Ecological Group advised national teams of hydro-biologists on the monitoring and evaluation of the effects of vector control on rivers. The vector control unit, in collaboration with the national teams of hydro-biologists and the Ecological Group, succeeded in protecting the environment while eliminating Riverblindness. Twenty years of larvicide spraying on rivers and streams has had no appreciable impact on the fish and invertebrate communities living within them. Studies have also shown that the number of aquatic species did not change as a result of this spraying.

Economic Rate of Return.
With the steadfast support of the international donor community and effective collaboration among the African participating countries as well as the sponsoring agencies, OCP has become recognized as one of the most successful programs in the history of development assistance. A cost-benefit analysis of OCP was performed in terms of net present value (NPV) and internal rate of return (IRR). The actual expenditures from 1974 through 1993 and projected expenditures from 1994 to 2002-which is the year in which OCP was brought to conclusion-are US$556 million in nominal terms and US$571 million in 1987 constant dollars.

OCP was able to produce several benefits in the region including improved health among adults, improved living environment, and additional agricultural output as a result of the extra oncho-freed labor force and land. The NPV of labor and land-related benefits together (assuming 85% labor participation and land utilization) over a 39 year project horizon (1974-2012) ranges between US$3,729 million and US$485 million in 1987 constant dollars at discount rates of 3% and 10%, respectively. Further, the estimated IRR under the same assumptions is on the order of 20%. Using a shorter project horizon (1974-2002) of 29 years yields an IRR of about 18%. These are highly respectable IRRs and represent some of the best economic returns among Bank projects over the years in virtually any sector.

Success.
The wide-ranging benefits of OCP include the following achievements:

  • 600,000 cases of blindness prevented
  • 40 million people are protected from infection by the disease
  • 18 million children, born in now-controlled areas, spared the risk of Riverblindness
  • 25 million hectares of land made safe for cultivation and resettlement
  • 5 million years of productive labor have been added to the economies of the eleven OCP countries (using traditional farming techniques and existing technology, this land can produce enough food to feed 17 million people)
  • Estimated economic rate of return of 20%

OCP's success was built on:

  • a clear objective
  • sound management
  • capable, knowledgeable staff
  • effective and feasible control methods (proven before operations began)
  • strong commitment of donors and participating countries over a long-term (20-year) and
  • decentralization by gradually delegating tasks and authority to lower levels, promoting ownership and commitment, contracting technical services to private companies, and gradually devolving control efforts to the affected countries

SIZs & MDSC.
To ensure control maintenance and to safeguard past achievement, OCP beneficiary countries relied on multi-disease surveillance, vector control, and ComDT. Through continuing donations of Mectizan by its manufacturer, Merck & Co, Inc., as well as financial support from a large pool of donors, OCP maintains reserve funds to continue operations in the five SIZs for the required five more years. Monitoring activities have been devolved to the national authorities, to be assisted through the establishment of a sub-regional multi-disease surveillance center at OCP Headquarters. The center will participate in the training of national epidemiologists, assist in the creation of national surveillance systems and collaborate with countries for operational research concerning surveillance. Currently, the remaining OCP staff, which is 99% African, is providing technical and logistical support to participating countries during this transitional period to ensure that they are capable of continuing residual Riverblindness control activities within the framework of their own national health systems.

OCP's headquarters and infrastructure are now being used for the West African Multidiesease Surveillance Center (MDSC). The intention of this center is to survey West Africa for Riverblindness and other prevalent diseases in the region, such as HIV/AIDS, malaria, and cerebral spinal meningitis. It will be responsible for communicating information for the control of epidemics, providing data for management of communicable disease programs, providing quality assurance to labs and diagnostic services, coordinating studies, offering specialized training, and providing continuous surveillance in support of the achievements of OCP.

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