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Defeating Onchocerciasis (Riverblindness) in Africa
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The Onchocerciasis Control Program (OCP)
The African Program For Riverblindness Control (APOC)
Community Distributed Treatment (ComDT) with Ivermectin
The Opportunity of ComDT - Add-on Interventions
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The Opportunity of ComDT-Add-On Interventions

A by-product of OCP and APOC’s success with ComDT of ivermectin is the drive it produces in communities to assume wide responsibility for healthcare. It also, however, provides communities with a platform for multi-disease control. OCP and APOC’s ComDT network offers a key entry point for many health interventions in the most remote, rural communities. The ComDT networks reach the poorest of the poor in areas where National Health Services are weak or non-existent. Prime targets for ComDT are:

  • Ivermectin and albendazole to halt transmission of highly disabling lymphatic filariasis (elephantiasis);
  • Vitamin A to prevent malnutrition, blindness, and death;
  • Praziquantel for control of widespread schistosomiasis; and
  • Information, Education, and Communication (IEC) and condom distribution to prevent HIV/AIDS and promote reproductive health
Lymphatic Filariasis (LF) causes kidney damage, physical disfigurement, and social ostracism. It is the fourth-leading cause of permanent disability world-wide. It has infected approximatly 43 million people in 37 countries in sub-Saharan Africa. All 30 countries which currently participate in APOC and in OCP are co-endemic with Riverblindness and LF. Ivermectin is effective in clearing the bloodstream of microfilarial infection with LF when combined with the drug albendazole. Accordingly, Merck & Co. announced the extension of their Mectizan donation program to control LF in Africa. Ivermectin will be given free of charge to control LF in every country in Africa where Riverblindness and LF co-exist. APOC has already begun co-distribution of ivermectin and albendazole for LF in Nigeria.


Vitamin A Deficiency is the leading cause of pediatric blindness and a major determinant of childhood mortality and maternal death. Under-five child mortality can be decreased by 25-35% through a six-month high-dose vitamin A capsule, which can be safely and efficiently distributed by community-based volunteers. Hellen Keller International and The Micronutrient Initiative (MI) have already begun co-distribution of vitamin A supplements through ComDT in Nigeria, southern Sudan, and Tanzania. Results show increased coverage of vitamin A supplementation from below 30% with routine health facility-based distribution to above 80% with ComDT. APOC and MI are, currently, working together to scale up this co-distribution of ivermectin and vitamin A supplements in other APOC countries, including Angola, Malawi, Tanzania, and Uganda.

Schistosomiasis is the second most prevalent tropical disease after malaria. Approximately 160 million people in sub-Saharan Africa are infected, making up 80% of the cases worldwide. Children are especially vulnerable to contracting schistosomiasis. Schistosomiasis progressively damages the bladder, intestines, liver, and kidneys, and often causes bladder cancer in advanced cases. It is present in much of sub-Saharan Africa and co-endemic with Riverblindness in many of the APOC countries. Praziquantel is safe, inexpensive, and effective in a single dose in treating all types of schistosomiasis. Currently, APOC has begun co-distribution of ivermectin and praziquantel in Nigeria and Uganda.

HIV/AIDS prevalence in Guinea is about 5% with a contraceptive access rate between 1-5%. Statistics show the unmet demand for contraceptives in Guinea reaches 25-30%. Guinean Family Planning Associations’ rural health services have only been able to reach approximately 500 villages nationwide, in the past. The OCP/SIZ ivermectin distribution network is able to reach 2,400 villages and 900,000 people with 3,800 community distributors. A rural health pilot project concerning HIV/AIDS and reproductive health is underway using the ComDT in Guinea. This project advocates for the protection against HIV/AIDS by contraceptive distribution and knowledge sharing that is passed down through the OCP/SIZ ivermectin distribution network.

Other project interventions that APOC is linking to the ComDT network include:

  • Guinea Worm intervention in Nigeria;
  • Immunizations for Polio, Measles, and others in Cameroon, Chad, DRC, southern Sudan, Tanzania, and Uganda;
  • Eye Care, including primary eye care and cataract identification, in Cameroon, Chad, DRC, Nigeria, and southern Sudan; and
  • Malaria bed net distribution in southern Sudan.

 

 

 

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